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Genes Might Explain Affinity to Fat or Sugar, Study Finds

Genes Might Explain Affinity to Fat or Sugar, Study Finds



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Disruption to MC4R pathway in mice led to greater fat consumption and lower sugar consumption

iStock / Thinkstock

Conclusions drawn from this study could help scientists to better understand obesity.

Turns out biology might be to blame for fat and sugar preferences, according to researchers from the University of Cambridge. They found that “a central molecular pathway may show significance in macronutrient preference in humans,” and in identifying this pathway, they can establish a direct link between specific genetic variants and food preferences, FoodNavigator reported.

This research could help to explain how people make choices about food and have “potential implications for a deeper understanding of obesity.”

The pathway that was analyzed involves the melanocortin-4 receptor (MC4R). In mice, disruption to this receptor leads them to eat more fat and, strangely enough, less sugar, which also held true in the human study that included 14 adults with a loss of function in the MC4R gene.

“By carefully testing [fat and sugar] in this study, and by testing a relatively rare group of people with the defective MC4R gene, we were able to show that specific brain pathways can modulate food preference,” said professor Sadaf Farooqi of University of Cambridge.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.


Can the Keto Diet Help Prevent or Manage Heart Disease?

The trendy diet is high in fat — but that doesn’t mean it will clog up your arteries. Still, cardiologists say there may be a better way to prevent heart conditions.

Some keto followers brag about how much butter and bacon they can eat. So if you have heart disease, are at risk for it, or are generally concerned about your heart health, you may be confused about whether the diet — made up of at least 70 percent fat and very few carbs depending on the version of keto you follow — could be for you. The short answer is that you may be able to try the keto diet but only under close supervision with a keto-knowledgeable doctor (and, ideally, a registered dietitian as well). For optimal heart health, many cardiologists are wary of the keto meal plan.